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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53d2afab2c7cc1c3e9fbc030ee3c22f04ddd23f6a7d2dcb21fb5cba1c0b331b' 
  AND token = 'hubJEfnKHqZS3IrucmcMK/T0wz08zUP+axdtXZlQMBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}