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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb1e84e5940b34392dc21c7e00496816adc0455d66db76418c5da3f4a9eb296' 
  AND token = 'oy0aFx9RYOFisQxFSXdlPPx+2gOlFkm/0NS8g388Dy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}