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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f82fbdfb27b7ec9c28d19d51116b53bb4a0b41c8970e12e90d5a9e81a0183813' 
  AND token = 'VjURolQQnIEq3lR34gfWXxsV3FeV2BM0Ytc1fQvelPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}