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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a7de48aff3bf28dd7c76b7a4bea84bf263c011ee47498309adcd41496d792f' 
  AND token = 'kY4ishu1FwWvw6hzvn0EgQoNcKwSu9W9360XOVwN0h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}