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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5657b45cf923e38f661e625bc508161f029f1060ca8a1b8d54c24f0de67b44e' 
  AND token = 'rgLd0CfGodBBRIeUulDwCYb/l5KrRH3hBE49vfBjCEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}