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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259b1cf923d5b8064b21781631cefa315d32f40a45f53d82daf078fe21a58ebe' 
  AND token = 'E9PbxxoNHopM3tXrmd8yNB2Vdr51rqmdn48bpq/bEYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}