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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed24e3425eff4ca4280ff7c989e6c50e57682c1f23e0f96ff5b83c27c43ec20' 
  AND token = 'GKDh4/5reEuHCI3/rtVhaK0WZRIT7zpBw0umhs++Md4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}