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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8e0581c31e2a3f0846693427538f9ecb5dc52cd420fc6808c79d4fcfc41f00' 
  AND token = '4zC5cjlBNeoET5G5m/lS0CFXplFRfvYINhCjKqfpFgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}