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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c3d26507af2e379659f360c8df72ceb97003912e9ef74e6e4291a70af17873' 
  AND token = 'UTNqstZ1ZLZ2ELLbYM+oAhlev7T3CYzF884T3AVLMWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}