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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78da134bd76f36c2fce19f4a87f1cdc39c4afb6a98d8868e2e4d29dfe6319834' 
  AND token = 'o2lcBs+6wa9oA3T2DVyUyY2h1bLhKwUN2r8CfX3I3wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}