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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e72d75da38d2cc522731a6fe046116fe01c6a682bcd45a9f6e6760f59e189fe' 
  AND token = 'xSRB77s+PTc3Vc45HTdwlIIxO4d9MU2jK1st5NRgmIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}