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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347a5e40ab51e907a1b7bb48592c02db3e34e614b2c2324a98d3ed9050699688' 
  AND token = 'Rm6XqCkvanmSlT+j395CYOMUVIZUN9oGQy8V1+RMFe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}