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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfc003df5240012355821291563f0abd33427f1167f391c736bf933ac5eaeb74' 
  AND token = 'NZ5MiLNRRG7y+QaN8qQzhqRrdjjApy1o3UUTt1w8nxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}