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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04353700b4c999ede7bd92635657b6a1334d2569e97c70b00bb62149996b231f' 
  AND token = '1sIY860zevAEagF0TiqvAklW/VC88vvX9sBLlVvMP5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}