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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f35480f10e9615329a8091d262773c7df21a220dd790b828ceedaad17a8ab6' 
  AND token = 'mhl/iwbEYEPzSQLx+0ofEnl0m7K7n0zPoK+F7wEQ/0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}