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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ba5a7c3d0e67a5fe4712791f72795486ee0599dfbc8df74e9ef756b0eb1157' 
  AND token = 'xQrgn4GExoMuKAHwEXSOQadS0JPlNL9wgCyaDs3sMR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}