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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b503aab565b5e8cca0dd122b70605daec78affb0f4e1667f8f4306f57f03808' 
  AND token = 'B5MN6IKDEmvy+R4qP5CVWpFp7Rf30ekblcMYyPw/+CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}