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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4c75ae14a8a54531743a1a6afa6bcd4d07997e3d1bedcbc5714442187b0f6c' 
  AND token = '+BTIECE6JSac6BM1aETNLvdWM7QRfAPMJ1CkWpTVF70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}