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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08c0d21e33d36b0058b1422d5aa252aa910c38048e6b2098cf0f9c97f593d36a' 
  AND token = 'KS/I2z2tDPAtQgOQ13O+V2kmn1lTH8pgGFFB/EE21Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}