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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeae32f8e9448390438a60c740f1e7e290fa48161b1d9d28ed25dde7d0351246' 
  AND token = '6UjmlQ23mg37vhisqVQ1nyFAGfREB3dZe7XFQ0PGHqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}