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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f661a9e02a6931783ccba6252b4955ccf1f6f946e1c7b85bf073616213fa53' 
  AND token = 'Ulc6LELyTQfJucJSSVZ4wJFrInLfzF8Xa+io4HF61MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}