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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a6735c1ce76009dfcf47110c3d0e0a4c8655fcbb23e21c5495f5c1d50767263' 
  AND token = 'JKJZGbJD9+Y/zO39ZMR7ckrf8iU30iEM8PwBMELBgfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}