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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13fbf9e5eec0119b148c5a6ecf3cce53630f223652f31253147db8bb16bcb5b' 
  AND token = 'rdg3OCt4qQAlH/DN9y0cc69ppiVprl410h/DI6WUWS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}