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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403d93adc03790c5674610ff00c08d5686b0a1972a8096922327b69cbcbff4a2' 
  AND token = 'AcwW2QXBRKQyZO4G8257tMEkKq/ImHs8sugodhGfJLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}