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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0103059e43ba7fc8cbf38bd3cc38c72b5be538c08b17c52c15e9b72147926b73' 
  AND token = 'vk1j3kWSBa7ycK3Xd/UlHZx3te7EbBz3CRst8cKYQ28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}