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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24cb80d1690cd17dc2dc5f1ef1510208153c5bd4daf97adae67731194a806b18' 
  AND token = 'NeokLg7uNZT+UgQceQ8wIxQ9ioLdtiaN6AVUM00md/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}