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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89d66ffa690511c204b6bbc0cdbe2fb8a730d29b6d47fd2c66514e9d1cd42dc8' 
  AND token = '8gsNxSsx+D3fA6IrP8vr7lf8k5I+UFizmDEwGQuhmW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}