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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd158ba2c6c34ac0dfd36539d548caee1e509338ad58d2072520725d85a6f4875' 
  AND token = '78yET+wq2giCHBLFCrb0AL32hO2oWuHg218fQ0Ozr5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}