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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1728267215ffca2aa6a5ab4fbdf1aa016b5cb077efb62cb150fea738b03224b' 
  AND token = 'xDwpVcGVaNfI6TTXLVRjC0/JlQRqv0gPlj1eiwORtOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}