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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed33baad35f48ac142a0975e4a4d017075ef9336f1433b68f8ccd846f7d85cd' 
  AND token = 'VJCPp0PQEOyIsATGLq17+WZP1wwj5kXzNIroY1s9wnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}