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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9647dbd386038c131e6837d4e8b6332487743b7146f0f7a8c027d38656cc8653' 
  AND token = 'dSiWF2OeKyzEnytlBiRgDtE1muGb0p2MpbFc9N/TXRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}