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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6f141de3f13f344be941964f96b11491ceb3a55b1a68c06aa0c43f2c23b03c' 
  AND token = 'WVR6plB7dGyQtgpVR9+2Rio4Gg4pzgn/5a7pbS3WF3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}