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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52374e1e49f1e460d58e0b658edbc4947ded2b8814ee3bf5f4854675384541c6' 
  AND token = '2hjiUHNFoqAiRByc+BAJROUBU8OP9Yml4iRuAr8RH6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}