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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37937d7525ed681f9650050b7a815cf30236eedf1382665f9375d2a4e3ee45f' 
  AND token = 'HFVTxBPKbf7ijyeovoNzm5iEl4fUIGw6Y1F2xMdGGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}