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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa172abbb6e697858a1f087a2b1a867fecf765aee8ffd5da5cd9526fd27985a' 
  AND token = 'S7rdIAxLqCFYAfYEZX9h5/QvvMaj80+lJAadU9bOzWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}