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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3e17da0df91500db7dc7f95207cf6f7c0657732cf5c4e5441c4164f2e4f100' 
  AND token = '7RHSa2BVFFbYsXHmMeRSd/a6EAzUkTOEcqzfLBLvXBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}