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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cd7cd29ed135ac45297d15cacec64a4867991a78b4276b5d922593553a8db6' 
  AND token = 'G0xK8boYzGAv2ed0iqIadfQeap8dea/9Fddh1kEgxxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}