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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71f89c28da6dbb8f0f0905b1ff9178db5326aaa0c43f6588fa035e30f030c066' 
  AND token = 'y6ZWSQmYfUMfuWW12d/PKMBHTOFzXFTWdekv+Wyhk3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}