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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4461f60cbc9e3af67dd875b2b203194e4654bd96aa5250c41a7649703e94e2' 
  AND token = 'QaT15YTPaviMZbPxSLjOZJzcNARcW0a8BP30RyflsSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}