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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221f91e6d95b3135ce0659d653590c281ab9b61eadca2c0b3e8f4667330331f7' 
  AND token = 'KF3w4PrWrY+Qb93uGvW5uljDTz6+5U3wFCymkKY9gm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}