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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d000c26c14934d433b44a1db7c0d5af7f7c93dd202961a56faa26df7b6a396' 
  AND token = 'PDOxRXZ748lh4n4FcHod8AirGfbfg144OSlfXFBZPfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}