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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc5229fd55f42e83c8e34fdaa7a5220daacc72833c24bd9a3b1f3985dd72a2c' 
  AND token = 'Y3a1ZREhB8tCJyZgOJL4xS29Oi1nbELseK0/65Mo1Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}