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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1eb0cb9098a5c59bb1091bebf17ca8d15cb7e9a84ec4bd5fd0410c50792728' 
  AND token = 'uz/+ZYLWTkKBn/z1DGQenszNiINlbhsHhc1ewEPnn7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}