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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5c47a1f2740a09adcd1787ecdf88bc129f0e5f14670ac6b9a61d7ee4e53c9f' 
  AND token = 'MKxSGnLZU/v5I5ZDAAB415o2HEPB/J9uOvmG/wROb3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}