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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab5bf32f6ca8045903eae72a561a904d9316bd10e54df27edd0c60c07dbef9f' 
  AND token = '8YTyPoArJvGCwJt8y2Z3pa6ZCDF1CK75YhKYIUvpypk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}