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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac0ed38dd7bcb6ac7cb02d00fd9f6b9c88a26e1627303501c499c7b6b177c364' 
  AND token = 'ZbNP7n8sIOYxHphRbZN/i8uVaEEaY4XAnXnM7XTgg+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}