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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b414d8e82708dcc442e71a0aa0c6b21d542335999c4669e1b1cd06075d0c0dfc' 
  AND token = 'qqrtqsjW1o2yKMSGJP5/U7wnKeLbBMz03TSThcOH0zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}