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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba53decadbe8b6b213035af82fd44bae66a59999ae90e755764ff6d83fd8eaf' 
  AND token = 'tJUkW1BCFnnsmTf+zMP56zRDvtA0mV8rVf1iYnBWUd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}