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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf1101f0b397c31d97e54efb9277a9f9999b8c8bd6fccea1703c9c04107526b' 
  AND token = 'UVk8mF3DLyjglxNHKAwfxCkBEx1FY3Q30Vge5f1wbdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}