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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a607a22806b392169663ef5fc01a1b473f66c4ea8af17ee0f479fdf21bb5d7d1' 
  AND token = 'Z1AqXpA/pkJIOF7i6tqzygjfY0L/1MbZlzuq//Bj3mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}